Neurokinin-1 Receptors

A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.

Also Known As:

Neurokinin 1 Receptor; Receptors, Neurokinin 1; Receptors, Neurokinin-1; NK-1 Receptor; Neurokinin-1 Receptor; Receptors, NK-1; Receptors, SP-P; SP-P Receptor; Substance P Receptor; Substance-P Receptor; Tachykinin Receptor 1; NK 1 Receptor; NK 1 Receptors; Neurokinin 1 Receptors; P Receptor, Substance; P Receptors, Substance; Receptor, NK-1; Receptor, Neurokinin-1; Receptor, SP-P; Receptor, Substance P; Receptor, Substance-P; Receptors, NK 1; Receptors, SP P; SP P Receptor; SP P Receptors; NK-1 Receptors; Receptors, Substance P; SP-P Receptors; Substance P Receptors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - G-Protein-Coupled Receptors: 4701
        Tachykinin Receptors: 168
        Neurokinin-1 Receptors: 913
      - Peptide Receptors: 1159
        Neuropeptide Receptors: 97
        Tachykinin Receptors: 168
        Neurokinin-1 Receptors: 913
      - Neurotransmitter Receptors: 562
        Neuropeptide Receptors: 97
        Tachykinin Receptors: 168
        Neurokinin-1 Receptors: 913

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Disease

Drug/Important Bio-Agent (IBA)